Search on: TRYPSIN INHIBITOR, KAZAL PANCREATIC 
Descriptors Found: 1
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Descriptor English:   Trypsin Inhibitor, Kazal Pancreatic 
Descriptor Spanish:   Inhibidor de Tripsina Pancreática de Kazal 
Descriptor Portuguese:   Inibidor da Tripsina Pancreática de Kazal 
Synonyms English:   Acidic Pancreatic Trypsin Inhibitor
Inhibitor, Tumor Associated Trypsin
Inhibitor, Tumor-Associated Trypsin
Kazal Pancreatic Trypsin Inhibitor
Pancreatic Secretory Trypsin Inhibitor
Pancreatic Secretory Trypsin Inhibitor, Kazal
Pancreatic Trypsin Secretory Inhibitor, Kazal
SPINK1
Serine Peptidase Inhibitor, Kazal Type 1
Serine Peptidase Inhibitor, Kazal-Type 1
Serine Protease Inhibitor Kazal Type 1
Serine Protease Inhibitor Kazal-Type 1
Trypsin Inhibitor Kazal Pancreatic
Trypsin Inhibitor, Pancreatic Secretory
Trypsin Inhibitor, Tumor Associated
Trypsin Inhibitor, Tumor-Associated
Tumor Associated Trypsin Inhibitor
Tumor-Associated Trypsin Inhibitor  
Tree Number:   D12.644.822.750.500
D12.776.124.050.850
D12.776.645.688.500
Definition English:   A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS. 
See Related English:   Kazal Motifs
 
History Note English:   91(75); was see under TRYPSIN INHIBITORS 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   27874 
Unique Identifier:   D014359 

Occurrence in VHL:
 

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